| Fall 2009 Henrik Kibak |  |
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Chapter 12 - Meiosis
Vocabulary:
| allele autosome chiasma crossing over diploid egg |
gametes gene haploid homolog homologous homology |
meiosis I meiosis II nondisjunction ploidy polyploidy sex chromosome |
sperm synapsis tetrad zygote |
You should be able to explain the following figures:
12.2, 12.4, 12.5, 12.7, 12.9, 12.11, 12.13, 12.14, 12.15, 12.16
Table 12.2, 12.4
Key Media: Meiosis (Flash Animation), Meiosis errors (Flash Animation)
Test Your Knowledge: #1, 2, 3, 4, 5, 6
Test Your Understanding: #3, 4, 5, 6
Applying Concepts to New Situations: #2
Chapter 13 - Mendel and the Gene
Vocabulary:
| allele blood type codominance crossing over dominant F1 generation F2 generation |
gene genetic distance genotype hemophilia heterozygous homozygous |
incomplete dominance linkage P generation phenotype pleiotropy polymorphic |
quantitative traits recessive recombinant sex-linkage testcross trait |
You should be able to explain the following figures:
13.3, 13.4, 13.5, 13.6, 13.7, 13.8, 13.10, 13.11, 13.12, 13.13, 13.14, 13.15, 13.16
Key Media: Punnett Squares (Flash Animation), Punnett/Meiosis (Flash Animation)
Test Your Knowledge: #1, 2, 3, 5, 7, 9
Genetics Problems: #11, 12, 17, 18, 22
Chapter 14 - DNA Synthesis & Repair
Vocabulary:
| complementary DNA continuous strand discontinous strand lagging strand leading strand DNA ligase |
DNA Polymerase I DNA Polymerase III endonuclease exonuclease genome helicase |
Okazaki fragments origin of replication primase primer replication fork sliding clamp |
SSB protein telomerase telomere topoisomerase transformation |
You should memorize Table 14.1
You should be able to explain the following figures:
Key Figures: Fig. 14.1, 14.2, 14.3, 14.4, 14.5, 14.6, 14.7, 14.9, 14.10, 14.11, 14.12, 14.13, 14.14, 14.15
Key Media: DNA Synthesis (Flash Animation)
Note that the Meselson-Stahl Experiment we covered briefly in class appears on many MCAT & GRE type exams (Figure 14.8)
Test Your Knowledge: #1, 2, 3, 4, 5, 6
Test Your Understanding: #2, 3, 4, 6 part 1
Chapter 15 - How Genes Work
Vocabulary:
| "central dogma of molecular biology" metabolic pathway RNA polymerase messenger RNA genetic screen |
reading frame transcription genetic code triplet code |
start codon stop codon translation codon |
Test Your Knowledge: #1 - 6
Test Your Understanding: #1, 2, 3, 4, 5, & 6
Applying Concepts to New Situations: #1, 2, & 4
Vocabulary:
| 5'-cap aminoacyl tRNA synthetase anti-codon wobble basal transcription factor coding DNA exon hairpin initiation factor |
intron molecular chaperones non-coding DNA point mutation poly(A) tail post-translational modification primary RNA transcript promoter sequence release factor |
ribosome RNA Polymerase I RNA Polymerase II RNA Polymerase III RNA splicing rRNA sense strand (non-template) Shine-Dalgarno sequence silent mutation |
snRNPs spliceosome TATA Box template strand transcription transcription termination signal translation tRNA |
This entire chapter is so important, and so much of biotechnology and molecular biology depends on understanding these concepts, that you should read it in its entirety... perhaps several times.
Key Figures: Almost alll figures are key! I guess you can ignore 16.11 & 16.13, but understand the rest.
Key Media: Transcription (Flash Animation), Translation (Flash Animation) Powerpoint (from class)
Test Your Knowledge: #1 - 6
Test Your Understanding: #2, 3, 4, & 6
Applying Concepts to New Situations: #1, & 3
Chapter 17 - Control of Gene Expression in Bacteria
Vocabulary:
| regulatory genes structural genes constitutive genes |
transcriptional control translational control post-translational control |
β-galactosidase lac permease (galactoside permease) operon |
gene expression polycistronic mRNA catabolite activator protein |
Key Figures: 17.1, 17.3, 17.4, 17.5, 17.6, 17.8, 17.9, 17.10, Box 17.1, 17.13, 17.14, 17.15, 17.18, 17.19
Key Media: Gene Expression (PowerPoint from class), The Lac/CAP System (Flash Animation)
Test Your Knowledge: #1, 2, 3, 4, & 6
Test Your Understanding: #2, 4
Applying Concepts to New Situations: #3 & 4
Chapter 18 - Control of Gene Expression in Eukaryotes
Vocabulary:
| alternative splicing basal transcription complex basal transcription factors regulatory transcription factors |
chromatin remodeling coactivator DNA regulatory sequences |
histones nucleosomes TATA-binding protein |
enhancer promoter-proximal elements silencer |
Key Figures: 18.1, 18.2, 18.4, 18.5, 18.7, 18.9, 18.10, 18.11, 18.13, 18.14, & 18.15
Key Media: Eukaryotic Gene Expression (Flash Animation)
Test Your Knowledge: #1-6
Test Your Understanding: #2, 3, 4, 5, & 6
Applying Concepts to New Situations: #1
Chapter 19 - Analyzing and Engineering Genes
Vocabulary:
| Agrobacterium tumefaciens biotechnology cDNA cDNA library DNA probe |
dideoxy sequencing genetic cloning genetic engineering genomic library plasmid |
polymerase chain reaction recombinant DNA technology restriction endonuclease reverse transcriptase |
sticky ends Taq polymerase T-DNA transformation |
Key Figures: 19.2, 19.3, 19.4, 19.5, 19.6, 19.7, 19.9, 19.10, 19.13, 19.17, 19.18, & Table 19.1 p. 406-407
Key Media: Constructing a cDNA Library (Flash Animation), PCR the "Polymerase Chain Reaction" (Flash Animation)
Test Your Knowledge: #1--3, 5 & 6
Test Your Understanding: #1, 3, & 5
Applying Concepts to New Situations: #4
Chapter 20 - Genomics
Vocabulary:
| alternative splicing DNA fingerprinting genomics proteomics |
lateral gene transfer LINEs SINEs tandem repeat |
microarray microsatellite minisatellite SNPs |
transposable element transposon |
Key Figures: 20.3, 20.5, 20.6, 20.7, 20.9, 20.10, 20.12
Key Media:
Test Your Knowledge: #1-6
Test Your Understanding: #1, 3, 4, & 5
Applying Concepts to New Situations: #4