CSUMB Bio 310L - Features of Soluble Proteins - Myoglobin Case Study

Lab #3 The objectives of this third lab are to: Use Cn3D and Clustal W to investigate the evolution of Hemoglobin from Myoglobin.           Here's the assignment: Which residues had to change in hemoglobin in order to form an alpha/beta dimer instead of a monomer as in myoglobin? Using the NCBI website find and retrieve the FASTA format of NP_005359 (Human myoglobin). Useful web links for this assignment: BLAST ClustalW Myoglobin sequence Beta Hemoglobin Alpha Hemoglobin 3HHB in PDB - This is a Cn3D file, so you right-click it and store it on your desktop. Then open it with Cn3D (see first lab). 2MM1 in PDB - This is a Cn3D file, so you right-click it and store it on your desktop. Then open it with Cn3D (see first lab). Hemoglobin - May 2003 Protein of the Month! Prepare a WORD document called myoglobin_hemoglobin.doc Save myoglobin_hemoglobin.doc to the 310 folder in your campus directory. Edit your campus/310/index.html to include a link to myoglobin_hemoglobin.doc